* Based on Rx option combinations (sphere, cylinder, axis and add) manufactured, across all soft lenses in sphere, toric and multifocal (including made to order), in silicone hydrogel and hydrogel from 4 main manufacturers. Includes daily disposable and monthly disposable contact lenses. Cosmetic and Photochromatic contact lenses not included. Multiple base curve variants not included.

^†Compared among CooperVision 1 day silicone hydrogel contact lenses. Data on file.

^‡ Warning: UV-absorbing contact lenses are not substitutes for protective UV-absorbing eyewear, such as UV-absorbing goggles or sunglasses, because they do not completely cover the eye and surrounding area. Patients should continue to use UV-absorbing eyewear as directed.

^§ Based on subjective ratings on application and after 1 month. Results of a prospective, double-masked, randomised, bilateral, crossover study comparing Avaira Vitality^R sphere contact lenses with a competitive reusable sphere lens.

^‖ compared to a single vision 1-day lens over a 3 year period

References:

1. CVI data on file, 2019.

2. Chamberlain P, et al. A 3-year randomized clinical trial of MiSight^® lenses for myopia control. Optom Vis Sci. (2019);96(8):556–567.

3. Cavet ME, et al. In vitro biocompatibility assessment of multipurpose contact lens solutions: Effects on human corneal epithelial viability and barrier function. Contact Lens and Anterior Eye. (2012);35(4):163-170.

4. Griffiths H. Clinical performance of the Bioclear family of lenses. Optician. 2008(3).

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6. CVI data on file, 1997, 1999, 2000, 2008, 2011, 2018.

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9. CVI data on file, 1997, 1999, 2000, 2008, 2011, 2018

10. CVI data on file 2011.

11. CVI data on file 2018: Short-term (2 hour) clinical evaluation with 28 subjects wearing fanfilcon A or comfilcon A, both CLs having been soaked overnight in AIOL.

12. CVI data on file 2012.

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14. CVI data on file, 2001.

15. CVI data on file, 1998 and 2012

16. CVI data on file.

17. CVI data on file, 2008.

18. CVI data on file, 1997.

19. Kim HL, et al. Modulation of protein adsorption by poloxamer 188 in relation to polysorbates 80 and 20 at solid surfaces. J Pharm Sci. (2014);103(4):1043–1049.

20. Coopervision data on file 1999.

21. Rasyid NQ, et al. Suspension stability and characterization of chitosan nanoparticle–coated ketoprofen based on surfactants oleic acid and poloxamer 188. Makara J. Sci. (2014);18(3):86-90.

22. Vibhute S, et al. Formulation and evaluation of tear substitutes. Int J Pharm Sci Rev Res. 2010;2(1).

23. Doughty MJ. Re-wetting, comfort, lubricant and moisturizing solutions for the contact lens wearer. Contact Lens and Anterior Eye (1999); 22(4):116-126.

24. Chiu G. Care and compliance in contact lens success. AOA Contact Lens and Cornea Section. 2009 Research paper.